Reference

Glossary.

Plain-language definitions for the technical terms used across this site.

7-OH: Short for 7-hydroxymitragynine. A naturally occurring alkaloid in the kratom plant and a potent μ-opioid receptor agonist. Trace amounts (under 0.05%) exist in raw kratom leaf; concentrated extracts marketed as "7-OH" products have far higher concentrations.
Mitragynine: The most abundant alkaloid in kratom leaf (typically 1.5–2.5% of dry weight). A partial μ-opioid receptor agonist with substantially different pharmacology than 7-OH despite being chemically related.
Pseudoindoxyl: Mitragynine pseudoindoxyl — a μ-opioid agonist derived from mitragynine, reported in animal studies to be more potent than 7-OH with a distinct receptor-bias profile.
DHM: Dihydromitragynine. A hydrogenated form of mitragynine. Limited published characterization; appears in some "next-generation" concentrated kratom products.
MGM-15 / MGM-16: Synthetic mitragynine analogs detected in adulterated supplements and seized samples. Not natural kratom alkaloids. Sometimes appear in products marketed under botanical names like "Cat's Claw."
μ-opioid receptor: The opioid receptor subtype targeted by morphine, oxycodone, and heroin — and also by 7-OH, pseudoindoxyl, MGM-15, MGM-16, and SR-17018. The pharmacological reason concentrated kratom-alkaloid products can produce dependence and withdrawal similar to traditional opioids.
Alkaloid: A naturally occurring nitrogen-containing organic compound. Plant alkaloids (caffeine, nicotine, morphine, mitragynine) often have potent pharmacological effects.
HPLC: High-performance liquid chromatography. The analytical technique used to quantify 7-OH, mitragynine, and other alkaloids in a product sample. SD Pharm Labs runs this for our lab-test program.
COA: Certificate of analysis. The lab's formal report of what was found in a sample, with quantitative values per analyte. Every lab result we publish includes the raw COA PDF.
$/mg: Price per milligram of 7-OH in a pack. Our headline unit-economics number. Lets you compare a 30mg single tablet against a 6,400mg bulk pack.
Total mg: Total milligrams of 7-OH (or other primary alkaloid) in a pack. Product packaging usually states this prominently.
Chain of custody: A documented record of who handled a sample and when, from sample collection through lab analysis. We require it for every lab test we publish.
SR-17018: An experimental synthetic μ-opioid receptor agonist developed in the Bohn lab at Scripps. Not a kratom alkaloid; included on this site because some users report using it adjacent to kratom-stop attempts.